교수

허익수

허익수 Huh, Iksoo

조교수
보건간호통계학 전공

학력 (Education)

서울대학교 통계학과 대학원 (석박사 통합)
서울대학교 통계학과 (학사)

경력 (Career)

서울대학교 간호학과 조교수
미국 조지아 공과대학교 생물학과 (박사 후 연구과정)
서울대학교 통계학과 (박사후 연구과정)

관심연구영역

유전역학, 후성유전학

연구업적

■ I Huh, I Mendizabal, T Park, SV Yi, (2018) Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals. Plos Computational Biology , doi.org/10.1371/journal.pcbi.1006451.
■ D Sun, I Huh, WM Zinzow-Kramer, DL Maney, SV Yi, (2018) Rapid regulatory evolution of a nonrecombining autosome linked to divergent behavioral phenotypes, Proceedings of the National Academy of Sciences of the United States of America, doi.org/10.1073/pnas.1717721115.
■ I Huh, X Wu, T Park, S Yi, (2017) Detecting differential DNA methylation from sequencing of bisulfite converted DNA of diverse species, Briefings in Bioinformatics, doi: 10.1093/bib/bbx077.
■ DW Lee, SW Han, Y Cha, JM Cha, HW Kim, J Lyu, H Han, H Kim, H Jang, D Bang, I Huh, T Park, JK Won, SY Jeong, KJ Park, GH Kang, TY Kim. (2017) Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer, Cancer, 123(18):3513-3523
■ YJ Kim, I Huh, JY Kim, et al., (2017) Integration of Traditional and Metabolomics Biomarkers Identifies Prognostic Metabolites for Predicting Responsiveness to Nutritional Intervention against Oxidative Stress and Inflammation, Nutrients, 9(3):233
■ C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, KJ Gaulton, C Ma, P Fontanillas, L Moutsianas, DJ McCarthy, MA Rivas, JRB Perry, XI Sim, TW Blackwell, NR Robertson, NW Rayner, P Cingolani, AE Locke, JF Tajes, HM Highland, J Dupuis, PS Chines, CM Lindgren, C Hartl, AU Jackson, H Chen, JR Huyghe, M van de Bunt, RD Pearson, A Kumar, M M?ller-Nurasyid, N Grarup, HM Stringham, ER Gamazon, J Lee, Y Chen, RA Scott, JE Below, P Chen, J Huang, MJ Go, ML Stitzel, D Pasko, SCJ Parker, TV Varga, T Green, NL Beer, AG Day-Williams, T Ferreira, T Fingerlin, M Horikoshi, C Hu, I Huh, et al, (2016), The genetic architecture of type 2 diabetes, Nature, 536(7614):41-47.
■ HR Chang, S Nam, J Lee, JH Kim, HR Jung, H Park, S Park, YZ Ahn, I Huh, et al., (2016) Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer, Oncotarget, 7(49):81435-81451
■ S Oh, I Huh, SY Lee, T Park, (2016) Analysis of multiple related phenotypes in genome-wide association studies, Journal of Bioinformatics and Computational Biology, 14(5): 1644005
■ S Ryu, I Huh, EY Cho, et al. (2016) Association Study of 60 Candidate Genes with Antipsychotic-induced Weight Gain in Schizophrenia Patients, Pharmacopsychiatry, 49(2):51-56.
■ SY Yang, I Huh, JH Baek, et al. (2015) Association between ST8SIA2 and the Risk of Schizophrenia and Bipolar I Disorder across Diagnostic Boundaries, Plos One, 10(9): e0139413
■ I Huh, S Oh, MS Kwon, T Park, (2015) An efficient stepwise, statistical test to identify multiple linked human genetic variants associated with specific phenotypic traits, Plos One 10(9): e0138700
■ Y Cho, S Ryu, I Huh, EY Cho, H Oh, YS Le, WK Lee, T Park, JS Kwon, KS Hong, (2015) Effects of genetic variations in NRG1 on cognitive domains in patients with schizophrenia and healthy subjects, Psychiatric Genetics 25(4):147-154
■ I Huh, T Park (2015) Multifactor dimensionality reduction analysis of multiple binary traits for gene-gene interaction Int. J. Data Mining and Bioinformatics, 14(4):293-304
■ EY Kim, SH Kim, SJ Rhee, I Huh, K Ha, J Kim, JS Chang, DH Yoon, T Park, YM Ahn, (2015) Relationship between thyroid-stimulating hormone levels and risk of depression among the general population with normal free T4 levels, Psychoneuroendocrinology, 58:114?119
■ JS Kim, TH Ha, JS Chang, YS Park, I Huh, J Kim, KS Hong, T Park, K Ha (2015), Seasonality and its distinct clinical correlates in bipolar II disorder, Psychiatry Res , 225(3):540-544
■ JH Baek, JS Kim, I Huh, K Lee, JH Park, T Park, K Ha, KS Hong, (2015) Prevalence, behavioral manifestations and associated individual and climatic factors of seasonality in the Korean general population, Comprehensive Psychiatry, 57:148?154
■ I Huh, SV Yi, T Park, (2015), A test for detecting differentially methylated regions, Bioinformatics and Biomedicine (BIBM), 2015 IEEE International Conference, 305-308.
■ HR Chang, S Nam, MC Kook, KT Kim, X Liu, H Yao, HR Jung, R Lemos Jr, HH Seo, HS Park, Y Gim, D Hong, I Huh, YW Kim, D Tan, CG Liu, G Powis, T Park, H Liang, YH Kim, (2014) HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer, GUT , 65(1):19-32
■ I Huh, X Yang, T Park, SV Y, (2014) Bis-class: a new classification tool of methylation status using bayes classifier and local methylation information BMC genomics, 15:608
■ JH Shin, T Park and, IS Huh (2013) Nursing Staffing and Quality of Life in Western New York Nursing Homes. Western Journal of Nursing Research, 36, 788-805.
■ JH Namkung, JE Lee, E Kim, IS Huh, T Park, ES Shin, EY Cho, JM Yang, (2013), Single nucleotide polymorphism in the FLT4 gene is associated with atopic dermatitis in Koreans , Cytokine, 62(1): 110-114
■ KI Kim, IS Huh, IW Kim, T Park, KS Ahn, SS Yoon, JH Yoon, JM Oh, (2013) Combined interaction of multi-locus genetic polymorphisms in cytarabine arabinoside metabolic pathway on clinical outcomes in adult acute myeloid leukaemia (AML) patients, Eur J Cancer.49(2):403-10.
■ HY Park, CR Kim, IS Huh, MY Jung, EY Seo, JH Park, DY Lee and JM Yang, (2013) Staphylococcus aureus colonization in acute and chronic skin lesions of patients with atopic dermatitis, Ann Dermatol. 25(4):410-416
■ I Huh, J Zeng, T Park, SV Yi, (2013) DNA methylation and transcriptional noise. Epigenetics & Chromatin, 6:9
■ JH Yoo, S Ryu, EY Cho, IS Huh, T Park, YS Lee, JS Kwon, KS Hong, (2012), Association Analyses of ST8SIA2 Genetic Polymorphisms with Schizophrenia in the Korean Population, Korean J Biol Psychiatry 2012;19:140-145
■ HY Park, IS Huh, DY Lee, JM Yang, (2011), Serum Zinc Levels in Patients with Atopic Dermatitis, Annals of Dermatology, 49(8):670-675
■ IS Kim, HJ Kim, HS Yang, E Kim, IS Huh, and JM Yang, (2011) IL-31 serum protein and tissue mRNA levels in patients with atopic dermatitis, Ann Dermatol, 23(4):468-473
■ IS Huh, S Oh, T Park, (2011), A chi-square test for detecting multiple joint genetic variants in genome-wide association studies, 2011 IEEE International Conference on Bioinformatics and Biomedicine, Workshops, 708-713, Atlanta, USA
■ S Lee, MS Kwon, IS Huh and, T Park (2011) CUDA-LR : CUDA-accelerated Logistic Regression Analysis Tool for Gene-Gene Interaction for Genome-Wide Association Study 2011 IEEE International Conference on Bioinformatics and Biomedicine, Workshops, 691-695, Atlanta, USA